This essay is in large part grounded in two earlier essays: The Nature of Evil and The Natural Mind. A brief summary of those two essays is included but reading the essays could also be helpful.
[Note: I use transgender in a broad sense and do not limit the term to persons who transition physically into the binary alternative to their assignment at birth (bodily sex). Personally, I make a distinction between sex identity (biological basis), gender identity (usually associated with a biological basis but is largely socio-cultural) and sexual orientation (biological basis). I consider each to be a separate factor in every individual, in whole or part. I also consider these factors to be variable and interactive producing a wide range of outcomes. While some outcomes are atypical relative to the norm, I consider all to be natural outcomes.]